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Oct 18 2022

E&E Seminar: “Understanding viral persistence in wild, Madagascar fruit bats” by Cara Brook (University of Chicago)

October 18, 2022

12:30 PM - 1:30 PM

a woman in a pink shirt next to program info


4289 SELE

Please join us on Oct. 18, 2022 at 12:30 pm for an E&E seminar featuring Dr. Cara Brook (University of Chicago)

Brook Lab

Host: Angie Salles

Abstract: Bats are reservoir species for zoonotic viruses that cause higher human case fatality rates than do viruses derived from any other bird or mammal host—including Ebola and Marburg filoviruses, Hendra and Nipah henipaviruses, and SARS, MERS, and SARS-CoV-2 coronaviruses. Intriguingly, bats appear to host these viruses without experiencing the significant pathology that infection incurs in other mammals. Globally, diverse bat populations have been shown to host rapidly transmitting RNA viruses with short generation times in isolated island populations well below known critical community sizes for related pathogens in human systems, thus calling into question the mechanisms that support viral persistence in wild bats. Understanding viral persistence in wild reservoir hosts is a necessary precursor to any effort to forecast future transmission events---including future zoonotic emergence. The Brook lab explores these questions of viral persistence in a wild, fruit bat ecosystem on the island nation of Madagascar, fitting mechanistic, epidemiological models to longitudinal time series data that they collect in the field. Ultimately, they aspire to uncover the mechanisms that drive the persistence and circulation of a suite of potentially zoonotic viruses in their threatened fruit bat hosts.


Emily Beaufort

Date posted

May 6, 2022

Date updated

Oct 11, 2022